Half-dose glucarpidase as efficient rescue for toxic methotrexate levels in patients with acute kidney injury.

Sandra HeuschkelTheresa KretschmannRaphael TeipelSimone von BoninStephan RichterSusanne QuickNael AlakelChristoph RölligEkaterina BalaianFrank KroschinskyHolger KnothMartin BornhäuserMalte von Bonin

Published in: Cancer chemotherapy and pharmacology (2021)

Half-dose glucarpidase seems to be effective in lowering MTX levels to concentrations manageable with continued intensified folinic acid rescue.

Keyphrases

acute kidney injury
high dose
low dose