Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation.

Ify R MordiBernadet T SantemaMariëlle KloostermanAnna-Maria ChoyMichiel RienstraIsabelle van GelderStefan D AnkerJohn G ClelandKenneth DicksteinGerasimos FilippatosPim van der HarstHans L HillegeMarco MetraLeong L NgWouter OuwerkerkPiotr PonikowskiNilesh J SamaniDirk J van VeldhuisenAeilko H ZwindermanFaiez ZannadAdriaan A VoorsChim C Lang

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2019)

Following beta-blocker uptitration, both achieved and change in heart rate were prognostically significant regardless of starting heart rate in SR, however, they were only significant in AF patients with high baseline heart rate.

Keyphrases

heart rate
atrial fibrillation
heart rate variability
blood pressure
heart failure
angiotensin converting enzyme
catheter ablation
left ventricular
left atrial appendage
coronary artery disease
percutaneous coronary intervention
newly diagnosed
acute coronary syndrome