Nanoparticle BAF312@CaP-NP Overcomes Sphingosine-1-Phosphate Receptor-1-Mediated Chemoresistance Through Inhibiting S1PR1/P-STAT3 Axis in Ovarian Carcinoma.

Ke GongYang DongLiting WangYi DuanJian YuYing SunMin BaiYourong Duan

Published in: International journal of nanomedicine (2020)

We found that BAF312@CaP-NPs act as an effective and selective delivery system for overcoming S1PR1-mediated chemoresistance in ovarian carcinoma by inhibiting S1PR1 and P-STAT3.

Keyphrases

signaling pathway
cell proliferation