Verteporfin-Loaded Anisotropic Poly(Beta-Amino Ester)-Based Micelles Demonstrate Brain Cancer-Selective Cytotoxicity and Enhanced Pharmacokinetics.
James G ShamulSagar R ShahJayoung KimPaula SchiapparelliCarla A Vazquez-RamosBen J LeeKisha K PatelAlyssa ShinAlfredo Quinones-HinojosaJordan J GreenPublished in: International journal of nanomedicine (2019)
Overall, this work highlights the promise of a biodegradable anisotropic micelle system to overcome multiple drug delivery challenges and enhance efficacy and safety for the treatment of brain cancer.