Hypertension and heart disease are associated with development of brain atrophy in multiple sclerosis: a 5-year longitudinal study.
Dejan JakimovskiS GandhiI PaunkoskiNiels P BergslandJesper HagemeierDeepa P RamasamyD HojnackiC KolbR H B BenedictBianca Weinstock-GuttmanRobert ZivadinovPublished in: European journal of neurology (2018)
Hypertension and heart disease contribute to advanced brain atrophy in MS patients. CVDs did not contribute to additional lesion accrual. CVD comorbidities in MS patients may contribute to neurodegenerative tissue injury that can be detected with brain MRI.
Keyphrases
- multiple sclerosis
- end stage renal disease
- white matter
- ejection fraction
- newly diagnosed
- blood pressure
- chronic kidney disease
- resting state
- mass spectrometry
- prognostic factors
- ms ms
- pulmonary hypertension
- functional connectivity
- computed tomography
- blood brain barrier
- subarachnoid hemorrhage
- diffusion weighted imaging