Increased FH-Risk-Score and Diabetes Are Cardiovascular Risk Equivalents in Heterozygous Familial Hypercholesterolemia.

Martine Paquette Bertrand Cariou Sophie Bernard Robert A Hegele Antonio Gallo Jacques Genest Mark Trinder Liam R Brunham Sophie Béliard Alexis Baass

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

This study strongly suggests that the observed risk of FH patients with diabetes, history of ASCVD, and FH-Risk-Score >20% is as high or higher than non-FH individuals with a history of ASCVD. More aggressive management should be recommended for these patients.

Keyphrases

end stage renal disease
type diabetes
ejection fraction
newly diagnosed
chronic kidney disease
cardiovascular disease
early onset
patient reported outcomes
adipose tissue
skeletal muscle
insulin resistance
weight loss
patient reported