Integrated proteomics, phosphoproteomics and metabolomics analyses reveal similarities among giant cell granulomas of the jaws with different genetic mutations.
Jéssica Gardone VitórioFilipe Fideles Duarte-AndradeThais Dos Santos Fontes PereiraMarcella Nunes Melo-BragaGisele André Baptista CanutoAdriana Nori de MacedoYuri Abner Rocha LebronVictor Rezende MoreiraLiza Figueiredo FelicoriLiséte Celina LangeLucilaine Valéria de Souza SantosMartin R LarsenCarolina Cavaliéri GomesHélder Antônio Rebelo PontesPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)
Despite some minor differences, our results revealed an overall similar molecular profile among the groups with different mutational profile at the metabolic, proteic, and phosphopeptidic levels.