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Epstein-Barr virus tegument protein BGLF2 in exosomes released from virus-producing cells facilitates de novo infection.

Yoshitaka SatoMasahiro YaguchiYusuke OkunoHanako IshimaruKen SagouSomi OzakiTakeshi SuzukiTomoki InagakiMiki UmedaTakahiro WatanabeMasahiro FujimuroTakayuki MurataHiroshi Kimura
Published in: Cell communication and signaling : CCS (2022)
The EBV tegument protein BGLF2 is encapsulated in exosomes and released by infected cells to facilitate the establishment of EBV infection. These findings suggest that tegument proteins support viral infection not only between the envelope and nucleocapsid, as well as in extraviral particles such as exosomes. Video abstract.
Keyphrases
  • epstein barr virus
  • diffuse large b cell lymphoma
  • induced apoptosis
  • mesenchymal stem cells
  • stem cells
  • cell cycle arrest
  • signaling pathway
  • oxidative stress
  • binding protein
  • sars cov
  • cell proliferation
  • bone marrow