Donor-derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation.

Ryo HanakiHidemi ToyodaShotaro IwamotoMari MorimotoDaisuke NakatoTakahiro ItoKaori NiwaKeishiro AmanoRyotaro HashizumeIsao TawaraMasahiro Hirayama

Published in: Immunity, inflammation and disease (2021)

We showed the protective effects of donor-derived M2 macrophages on GVHD and improved survival in a model of HSCT. Our data suggest that donor-derived M2 macrophages offer the potential for cell-based therapy to treat GVHD.

Keyphrases

allogeneic hematopoietic stem cell transplantation
acute myeloid leukemia
acute lymphoblastic leukemia
cell therapy
stem cells
big data
artificial intelligence
free survival
human health
hematopoietic stem cell