Homoharringtonine is synergistically lethal with BCL-2 inhibitor APG-2575 in acute myeloid leukemia.
Wenwen WeiShujuan HuangQing LingShihui MaoYu QianWenle YeFenglin LiJiajia PanXiangjie LinJiansong HuangXin HuangYifan ZhaiJie SunJie JinPublished in: Journal of translational medicine (2022)
Our results provide an effective AML treatment strategy through combination of APG-2575 and HHT, which is worthy of further clinical research.