A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT).
Hans L TillmannAyako SuzukiMichael MerzRichard HermannDon C RockeyPublished in: PloS one (2022)
DILI-CAT is a data-driven, diagnostic tool built to define drug-specific phenotypes for DILI adjudication. The data provide proof of principle that a drug-specific, data-driven causality assessment tool can be developed for different drugs and raise the possibility that such a process could enhance causality assessment methods.