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Evaluation of cannabidiol's inhibitory effect on alpha-glucosidase and its stability in simulated gastric and intestinal fluids.

Hang MaHuifang LiChang LiuNavindra P Seeram
Published in: Journal of cannabis research (2021)
CBD showed moderate inhibitory effect against yeast α-glucosidase activity and was stable in gastric and intestinal fluids. However, further studies on CBD's anti-α-glucosidase effects using cellular and in vivo models are warranted to support its potential application for the management of type II diabetes mellitus.
Keyphrases
  • molecular docking
  • type diabetes
  • metabolic syndrome
  • molecular dynamics simulations
  • saccharomyces cerevisiae