Prevalence of Mutations in Mendelian Stroke Genes in Early Onset Stroke Patients.

Hong Kyun ParkKeon-Joo LeeJong-Moo ParkKyusik KangSoo Joo LeeJae Guk KimJae-Kwan ChaDae-Hyun KimMoon-Ku HanJihoon KangBeom Joon KimTai Hwan ParkMoo-Seok ParkKyung Bok LeeJun LeeKeun-Sik HongYong-Jin ChoByung-Chul LeeKyung-Ho YuMi-Sun OhJoon-Tae KimKang Ho ChoiDong-Eog KimWi-Sun RyuJay Chol ChoiJee-Hyun KwonWook-Joo KimDong-Ick ShinSung Il Sohn Jeong-Ho HongJuneyoung LeeKyunghoon LeeJunghan SongJoon Seol BaeHyun Sub CheongStéphanie DebetteHee Joon Bae

Published in: Annals of neurology (2022)

CRGVs in 15 Mendelian stroke genes may not be uncommon in the young stroke population. The majority of patients with CRGVs did not have typical features of the corresponding monogenic disorders. Clinical implications of having CRGVs or VUSs should be explored. ANN NEUROL 2023.

Keyphrases

early onset
atrial fibrillation
late onset
genome wide
risk factors
bioinformatics analysis
dna methylation
genome wide analysis
neural network