At the onset of injury, vessel and matrix disruption lead to the generation of an inflammatory response: inflammatory cells are recruited to the injury site where they differentiate, activate, and/or polarize to secrete cytokines for the purposes of cell signaling and cell recruitment. This process is altered by age and by sex. Bone fracture healing is heavily influenced by the presence of inflammatory cells and cytokines within the healing tissue.
Keyphrases
- induced apoptosis
- inflammatory response
- cell cycle arrest
- single cell
- oxidative stress
- cell therapy
- endoplasmic reticulum stress
- stem cells
- bone mineral density
- signaling pathway
- mesenchymal stem cells
- lipopolysaccharide induced
- bone marrow
- body composition
- hip fracture
- lps induced
- toll like receptor
- soft tissue
- postmenopausal women