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Model-dependent contributions of FXII and FXI to venous thrombosis in mice.

Steven Philip GroverTatianna M OlsonBrian C CooleyNigel Mackman
Published in: Journal of thrombosis and haemostasis : JTH (2020)
Collectively, these data indicate that FXII and FXI contribute to the size of venous thrombosis in models with blood flow and thrombus composition in a stasis model. This study also demonstrates the importance of using multiple mouse models to assess the role of a given protein in venous thrombosis.
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