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Acquired aplastic anemia complicated with anti-glomerular basement membrane disease successfully treated with immunosuppressive therapy: a case report.

Kenji MatsuiWataru KamataYasuhiro MochidaKunihiro IshiokaHidekazu MoriyaSumi HidakaTakayasu OhtakeYotaro TamaiShuzo Kobayashi
Published in: BMC nephrology (2022)
We report the first case of acquired AA complicated with anti-GBM disease in an elderly woman with HLA-DR15, which was successfully treated with immunosuppressive therapy (IST). This report is valuable not only because it shows they may co-occur, but also because it provides a therapeutic option for this complex condition. It was also suggested that pancytopenia in patients with anti-GBM disease recalls serious hematologic diseases including AA that require immediate treatment based on bone marrow examination.
Keyphrases
  • bone marrow
  • mesenchymal stem cells
  • chronic kidney disease
  • stem cells
  • case report
  • middle aged
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • replacement therapy