Pulp inflammation induces Kv1.1 K+ channel down-regulation in rat thalamus.

Hiroki MuranoTomoatsu KanekoSu Yee Myo ZawPhyo Pyai SoneZar Chi Thein ZawYamato OkadaMitsuhiro SunakawaKen-Ichi KatsubeTakashi Okiji

Published in: Oral diseases (2021)

MO induced the transient down-regulation of Kcna1, transiently reduced the density of Kv1.1-expressing axons, and increased astrocytes in thalami within 1 hr of pulpal application. These results suggest central sensitization represented by neuronal hyperexcitability and astrocyte activation.

Keyphrases

oxidative stress
diabetic rats
cerebral ischemia
image quality
high glucose
dual energy
deep brain stimulation
magnetic resonance imaging
computed tomography
contrast enhanced
transition metal