Bromodomain-containing 4 is a positive regulator of the inflammatory cytokine response in the gut.
Eleonora FranzèFederica LaudisiClaudia MarescaAntonio Di GraziaAndrea IannucciTeresa PacificoAngela OrtenziGiuseppe SicaElisabetta LolliCarmine StolfiIvan MonteleoneGiovanni MonteleonePublished in: Journal of Crohn's & colitis (2024)
This is the first study showing the up-regulation of BRD4 in IBD and suggesting the role of such a protein in the positive control of the inflammatory cytokine response in the gut.