Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson's disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity.
Rodney C P GoMichael J CorleyG Webster RossHelen PetrovitchKamal H MasakiAlika K MaunakeaQimei HeMaarit I TiirikainenPublished in: BMC neuroscience (2020)
These results suggest that distinct DNA methylation biomarker profiles related to environmental exposures in PD cases with previous exposure can be found in both brain and blood.