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Establishment of Cell-Based Assay System for Evaluating Cytotoxic Activity Modulated by the Blockade of PD-1 and PD-L1 Interactions with a Therapeutic Antibody.

Haruka HirosakiYosuke MaedaMasahiro Takeyoshi
Published in: Immunological investigations (2023)
The newly established cell-based assay system can quantitatively evaluate the modulating effect of PD-1/PD-L1 immune checkpoint inhibitors by measuring cytotoxic activity, playing an important role in antitumor effects as innate immunity.
Keyphrases
  • single cell
  • high throughput
  • cell therapy
  • signaling pathway