Tumor development in Japanese patients with Lynch syndrome.

Chiaki SaitaTatsuro YamaguchiShin-Ichiro HoriguchiRin YamadaMisato TakaoTakeru IijimaRika WakaumeTomoyuki ArugaTaku TabataKoichi Koizumi

Published in: PloS one (2018)

Gastric cancer incidence was high in Japanese patients with LS and associated with H. pylori infection. MMR protein deficiency caused the development of malignant tumors in LS patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
risk factors
binding protein
small molecule
protein protein
replacement therapy