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Mesenchymal stromal cells for the prophylaxis and treatment of graft-versus-host disease-a meta-analysis.

Cynthia Morata-TarifaMaría Del Mar Macías-SánchezAntonio Gutiérrez-PizarrayaRosario Sanchez-Pernaute
Published in: Stem cell research & therapy (2020)
Our meta-analysis indicates that allogeneic MSC could be instrumental for the prophylaxis and treatment of GvHD. Future trials should investigate the effect of the administration of MSC as an adjuvant therapy for the treatment of patients with GvHD from the onset of the disease.
Keyphrases
  • systematic review
  • bone marrow
  • stem cell transplantation
  • low dose
  • combination therapy
  • allogeneic hematopoietic stem cell transplantation
  • acute myeloid leukemia
  • high dose