Human sorting nexin 2 protein interacts with Influenza A virus PA protein and has a negative regulatory effect on the virus replication.

Tuğba Koçmar Elif ÇaĞlayan Erkan Rayaman Kyosuke Nagata Kadir Turan

Published in: Molecular biology reports (2021)

This study revealed that the SNX2 and PA protein interact with each other in both yeast and HEK293 cells, and the SNX2 has a negative regulatory function on the virus replication. However, more knowledge is required to elucidate the action mechanism of the SNX2 on the influenza A virus replication at the molecular level.

Keyphrases

binding protein
protein protein
transcription factor
endothelial cells
induced apoptosis
amino acid
healthcare
small molecule
signaling pathway
oxidative stress
cell proliferation
single molecule