Role of Small Moiety of a Large Ligand: Tyrosine Templated Copper Nanoclusters.

To explore the underlying formation mechanism of luminescent metal nanoclusters (NCs) using a small moiety such as amino acids (outside the milieu of a protein environment) as templates, herein we report blue-emitting copper nanoclusters (CuNCs) using l-tyrosine (l-Tyr) as a capping agent as well as a reducing agent. We also demonstrate the effect of an in situ fibrillation of Tyr on the luminescence and structural properties of NCs. Fluorescence studies along with microscopic imaging revealed the rapid formation of a dityrosine (di-Tyr) moiety in an alkaline medium followed by an aggregated "Tamarix dioica leaf"-like fibrillar pattern along with CuNCs. Our present investigation delineates the role played by π-π interactions in the formation of the fibrillar structures. We substantiated the fundamentals of using a small molecule of a large ligand that can serve as a template and also show how these NCs once formed destroy the fibrils of di-Tyr as a function of time.