Cysteine protease of Clonorchis sinensis alleviates DSS-induced colitis in mice.

Xiaoying XieZhanshuai WuYuhong WuJing LiuXinyuan ChenXiaoqian ShiCaiheng WeiJiasheng LiJiahui LvQing LiLili TangShanshan HeTingzheng ZhanZeli Tang

Published in: PLoS neglected tropical diseases (2022)

Both rCsCP and CsCA showed good therapeutic effects on the treatment of acute colitis, but rCsCP is a better choice. rCsCP is a safe, effective, readily available and promising therapeutic agent against IBD mainly by activating innate immunity and regulating the IL-12/IL-23r axis.

Keyphrases

liver failure
signaling pathway
ulcerative colitis
respiratory failure
intensive care unit
hepatitis b virus
adipose tissue
decision making
replacement therapy