Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy.
Alicia C McDonaldManish ViraVonn WalterJing ShenJay D RamanMartin G SandaDattatraya PatilEmanuela TaioliPublished in: The Prostate (2019)
There was no circulating miRNA associated with high-grade prostate cancer at biopsy after adjusting for age and multiple comparisons. Nevertheless, relationships between these circulating miRNAs and high-grade prostate cancer were observed, which suggest them as promising prostate cancer biomarkers. Further investigation in a larger cohort may provide insight into their diagnostic potential for aggressive prostate cancer.