An LC-MS/MS assay for analysis of equilibrium angiotensin II in human serum.

Laura Bernstone Joanne E AdawayBrian G Keevil

Published in: Annals of clinical biochemistry (2021)

An LC-MS/MS assay for eqAng II has been developed which shows promise as an alternative screening test for primary hyperaldosteronism. Compared to renin assays, it is quicker, simpler and less likely to be affected by anti-hypertensive medications. Further clinical validation in hypertensive patients would be required prior to implementation.

Keyphrases

angiotensin ii
hypertensive patients
blood pressure
angiotensin converting enzyme
high throughput
vascular smooth muscle cells
primary care
healthcare
molecular dynamics
molecular dynamics simulations
machine learning