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Purification and enzymatic characterization of a novel metalloprotease from Lachesis muta rhombeata snake venom.

Francielle Almeida CordeiroBárbara Marques CoutinhoGisele Adriano WiezelKarla de Castro Figueiredo BordonCristiane Bregge-SilvaNathalia Gonsales Rosa-GarzonHamilton CabralBeatrix UeberheideEliane Candiani Arantes
Published in: The journal of venomous animals and toxins including tropical diseases (2018)
The purification procedure achieved a novel pure highly active metalloprotease from LmrV. This new molecule can help to understand the metalloproteases mechanisms of action, the Lachesis envenoming, as well as to open new perspectives for its use as therapeutic tools.
Keyphrases
  • minimally invasive
  • hydrogen peroxide
  • recombinant human