Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations.

Hartmut Döhner Courtney D D DiNardo Andrew H Wei Bob LöwenbergFrederick AppelbaumCharles F CraddockHervé DombretBenjamin L EbertPierre FenauxLucy A GodleyRobert P HasserjianRichard A LarsonRoss L LevineYasushi MiyazakiDietger NiederwieserGert J OssenkoppeleChristoph Röllig Sierra JorgeEytan M SteinMartin S TallmanHwei-Fang TienJian-Xiang Wang Agnieszka Świątek

Published in: Blood (2024)

The European LeukemiaNet (ELN) genetic risk classifications were developed based on data from younger adults receiving intensive chemotherapy. Emerging analyses from patients receiving less-intensive therapies prompted a proposal for an ELN genetic risk classification specifically for this patient population.

Keyphrases

machine learning
genome wide
deep learning
copy number
squamous cell carcinoma
case report
radiation therapy
big data