Lipid-based solubilization technology via hot melt extrusion: promises and challenges.
Ožbej ZupančičMartin SpoerkAmrit PaudelPublished in: Expert opinion on drug delivery (2022)
HME is a continuous, solvent-free, cost-effective, and scalable technology for manufacturing solid supersaturable SEDDS. Several critical formulations and process parameters for successfully preparing SEDDS via HME are identified.
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