Neurophysiological outcomes that sustained clinically significant improvements over 3 years of physiologic ECAP-controlled closed-loop spinal cord stimulation for the treatment of chronic pain.
Nagy A MekhailRobert M LevyTimothy Ray DeerLeonardo KapuralSean LiKasra AmirdelfanCorey W HunterSteven M RosenShrif J CostandiSteven M FalowskiAbram H BurgherJason E PopeChristopher A GilmoreFarooq A QureshiPeter S StaatsJames ScowcroftTory McJunkinChristopher K KimMichael I YangThomas StaussRichard RauckRui V DuarteNicole SolidayAngela LeitnerErin HansonZhonghua OuyangDave MuganLawrence PoreePublished in: Regional anesthesia and pain medicine (2024)
The results suggest that a physiological adherence to supra-ECAP threshold therapy that generates pain inhibition provided by ECAP-controlled CL-SCS leads to durable improvements in pain intensity with no evidence of loss of therapeutic effect through 36-month follow-up.