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Neurophysiological outcomes that sustained clinically significant improvements over 3 years of physiologic ECAP-controlled closed-loop spinal cord stimulation for the treatment of chronic pain.

Nagy A MekhailRobert M LevyTimothy Ray DeerLeonardo KapuralSean LiKasra AmirdelfanCorey W HunterSteven M RosenShrif J CostandiSteven M FalowskiAbram H BurgherJason E PopeChristopher A GilmoreFarooq A QureshiPeter S StaatsJames ScowcroftTory McJunkinChristopher K KimMichael I YangThomas StaussRichard RauckRui V DuarteNicole SolidayAngela LeitnerErin HansonZhonghua OuyangDave MuganLawrence Poree
Published in: Regional anesthesia and pain medicine (2024)
The results suggest that a physiological adherence to supra-ECAP threshold therapy that generates pain inhibition provided by ECAP-controlled CL-SCS leads to durable improvements in pain intensity with no evidence of loss of therapeutic effect through 36-month follow-up.
Keyphrases
  • chronic pain
  • spinal cord
  • pain management
  • neuropathic pain
  • spinal cord injury
  • stem cells
  • high intensity
  • glycemic control
  • combination therapy
  • weight loss