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Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline.

Audrey BuiJared LiuJulie HongEdward HadelerMegan MoscaNicholas BrownstoneWilson Liao
Published in: Journal of psoriasis and psoriatic arthritis (2021)
Through Pi, we identified data-driven candidate therapeutic gene targets and pathways for psoriasis and PsA. Given the sparse PsA specific genetic studies and PsA specific drug targets, this analysis could prove to be particularly valuable in the pipeline for novel psoriatic therapies.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • rheumatoid arthritis
  • ankylosing spondylitis
  • disease activity
  • copy number
  • drug induced
  • gene expression
  • dna methylation
  • genome wide identification