Association of peripheral immunity with cognition, neuroimaging, and Alzheimer's pathology.

Jia-Hui HouYa-Nan OuWei XuPeng-Fei ZhangLan TanJin-Tai Yunull null

Published in: Alzheimer's research & therapy (2022)

We revealed that two types of peripheral immune cells (NEU and LYM) and the ratio of these two cell types (NLR) had associations with cognition, neuroimaging, and AD pathology. The associations might be mediated by Aβ and tau pathology.

Keyphrases

single cell
mild cognitive impairment
white matter
cell therapy
stem cells
multiple sclerosis
cerebrospinal fluid
mesenchymal stem cells
bone marrow