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The effect of fixed and functional remodeling on conduction velocity, wavefront propagation and rotational activity formation in AF.

Shohreh HonarbakhshCaterina Vidal HorrachPier D LambiaseCaroline H RoneyRoss J Hunter
Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
CV dynamics are impacted by the degree of scar. CV heterogeneity and functional remodeling impacts wavefront propagation in SR and rotational activity burden in AF. This study provides insight to the pathophysiology of AF and identifies potential novel ablation targets.
Keyphrases
  • atrial fibrillation
  • genome wide
  • blood flow
  • dna methylation
  • gene expression
  • wound healing