Muscle mitochondrial function is impaired in adults with type 1 diabetes.
Daniel GottliebLayla A AbushamatKristen J NadeauJudith G RegensteinerJane E B ReuschKalie L TommerdahlJohn RiceLeslie A KnaubCynthia M F MonacoThomas J HawkeChristopher G R PerryMelanie G CreeIrene E SchauerPublished in: Journal of diabetes and its complications (2024)
The in-vivo analysis demonstrates that adults with type 1 diabetes have mitochondrial dysfunction. This builds on previous research showing in-vivo mitochondrial dysfunction in youths with type 1 diabetes and suggests that defects in substrate or oxygen delivery may play a role in in-vivo dysfunction.
Keyphrases