Genetic Predisposition to Type 2 Diabetes and Insulin Levels Is Positively Associated With Serum Urate Levels.

Jiahao ZhuLingling SunJing YangJiayao FanLap Ah TseYingjun Li

Published in: The Journal of clinical endocrinology and metabolism (2021)

This study provides supportive evidence on causal associations of T2D and fasting insulin with serum urate concentrations and a suggestive association of fasting insulin with risk of gout. Future research is required to examine the underlying biological mechanisms on such relationships.

Keyphrases

type diabetes
glycemic control
blood glucose
insulin resistance
cardiovascular disease
uric acid
skeletal muscle
gene expression
copy number