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Altered Patterns of Brain Glucose Metabolism Involve More Extensive and Discrete Cortical Areas in Treatment-resistant Schizophrenia Patients Compared to Responder Patients and Controls: Results From a Head-to-Head 2-[18F]-FDG-PET Study.

Felice IasevoliLuigi D'AmbrosioMariateresa CiccarelliAnnarita BaroneValeria GaudieriSirio CocozzaGiuseppe PontilloArturo BrunettiAlberto CuocoloAndrea de BartolomeisSabina Pappatà
Published in: Schizophrenia bulletin (2022)
These data indicate that, in TRS patients, altered metabolism involved discrete brain regions not found affected in nTRS, possibly indicating a more severe disrupted functional brain network associated with disorganization symptoms.
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