Summary of the clinical practice manual for late-onset hypogonadism.
Hisamitsu IdeYuko AkehiShinichiro FukuharaShin OhiraSumito OgawaTomoya KataokaHiroshi KumagaiKo KobayashiAkira KomiyaKazuyoshi ShigeharaTakahiro SyutoJintetu SohMakito TanabeHisanori TaniguchiKoji ChibaKazuhito MatsushitaYozo MitsuiTakahiro YoneyamaTomoya ShirakawaYasuhisa FujiiHiroaki KumanoHajime UeshibaToshiyasu AmanoHaruaki SasakiSeiji MaedaAtsushi MizokamiKazuhiro SuzukiShigeo HoriePublished in: International journal of urology : official journal of the Japanese Urological Association (2023)
Testosterone plays an important role in maintaining both physical and mental function. Age-related testosterone depletion contributes to the development of angina, arteriosclerosis, obesity, metabolic syndrome, dementia, frailty, and a range of other conditions. A condition involving age-related testosterone depletion and the associated clinical symptoms is defined as late-onset hypogonadism (LOH). LOH is treated by testosterone replacement therapy. Indications for testosterone replacement therapy are determined by evaluating symptoms and signs.
Keyphrases
- replacement therapy
- late onset
- smoking cessation
- metabolic syndrome
- early onset
- clinical practice
- insulin resistance
- type diabetes
- coronary artery disease
- mild cognitive impairment
- coronary artery
- cardiovascular disease
- sleep quality
- percutaneous coronary intervention
- uric acid
- weight gain
- depressive symptoms
- acute coronary syndrome
- high fat diet induced