Shear Stress in Bone Marrow has a Dose Dependent Effect on cFos Gene Expression in In Situ Culture.

Kimberly J CurtisThomas R CoughlinMary A VarsanikGlen L Niebur

Published in: Cellular and molecular bioengineering (2019)

The results suggest that the shear stress due to interactions between marrow cells induces a mechanobiological response. Identification of marrow cell mechanotransduction pathways is essential to understand healthy and pathological bone adaptation and remodeling.

Keyphrases

gene expression
bone marrow
induced apoptosis
cell cycle arrest
mesenchymal stem cells
single cell
dna methylation
cell therapy
bone mineral density
endoplasmic reticulum stress
stem cells
cell death
cell proliferation
body composition