Mesenchymal stromal/stem cells promote intestinal epithelium regeneration after chemotherapy-induced damage.

Bahar Yetkin-Arik Suze A Jansen Suzy Varderidou-Minasian Bart WestendorpK-P SkarpA F Maarten Altelaar Caroline A Lindemans Magdalena J Lorenowicz

Published in: Stem cell research & therapy (2024)

Collectively, we demonstrate that our in vitro co-culture system is a new valuable tool to facilitate the investigation of the molecular mechanisms behind the therapeutic effects of MSCs on damaged intestinal epithelium. This could benefit further optimization of the use of MSCs in HSCT patients.

Keyphrases

stem cells
mesenchymal stem cells
chemotherapy induced
end stage renal disease
bone marrow
newly diagnosed
ejection fraction
peritoneal dialysis
umbilical cord
oxidative stress
prognostic factors
cell therapy
patient reported