Graphene nano-ribbon based high potential and efficiency for DNA, cancer therapy and drug delivery applications.
Seyyed Mojtaba MousaviSadaf SoroshniaSeyyed Alireza HashemiAziz BabapoorYounes GhasemiAmir SavardashtakiAli Mohammad AmaniPublished in: Drug metabolism reviews (2019)
In this article, graphene oxide Nano ribbons (GONRs) and its high potential for using in medical fields have been reviewed. Recently, Graphene Nano ribbons (GNRs) has been a field of interest in biological methods and disease treatment such as drug delivery, DNA applications, and photothermal cancer therapies. GNRs demonstrate more efficient properties rather than other graphene-based Nanomaterials due to their larger surface area. These novel properties made them into a remarkable substitute material for biological fields as they have different cytotoxic effects and almost nontoxic to human health and the environment. In this study, some of the significant effects of GNRs such as Geno toxicity effects in human mesenchymal stem cells, DNA assembly, drug delivery agents, and the use of PEGylated GNRs in photothermal cancer therapy has been investigated.
Keyphrases
- cancer therapy
- drug delivery
- human health
- circulating tumor
- risk assessment
- mesenchymal stem cells
- drug release
- single molecule
- cell free
- climate change
- endothelial cells
- healthcare
- room temperature
- stem cells
- nucleic acid
- squamous cell carcinoma
- oxidative stress
- atomic force microscopy
- young adults
- induced pluripotent stem cells
- cell therapy
- combination therapy