IL-17 Mildly Rescued the Impaired Proliferation of Alveolar Epithelial Cells Induced by LCN2 Overexpression.

Tingting Lv Ziliang HouKaiyuan YangJinxiang Wang

Published in: Canadian respiratory journal (2024)

The results revealed the reversed effect of IL-17 on the impaired proliferative capacity of the alveolar epithelium induced by LCN2 overexpression. The target alveolar epithelial cells regulated by this process were AT2 cells, providing new clues for alveolar epithelium repair after injury and the treatment of lung injury diseases.

Keyphrases

induced apoptosis
cell proliferation
transcription factor
signaling pathway
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
combination therapy
pi k akt