Diagnostic accuracy of interleukin-6, interleukin-10 and tumor necrosis factor alpha cytokine levels in patients with mild cognitive impairment: systematic review and meta-analysis.
Alana Mara Inácio de AquinoKedma Anne Lima GomesLetícia Lorena Melo de BritoLuciana Domingos de LimaEneas Ricardo de Morais GomesSuellen Mary Marinho Dos Santos AndradePublished in: Dementia & neuropsychologia (2024)
These findings do not support the involvement of inflammatory biomarkers for detection of MCI, although significant heterogeneity was observed. More studies are needed to evaluate the role of these cytokines in MCI, as well as in other stages of cognitive decline and all-cause dementias.