Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies.

Emily G OakesEilish DillonKatherine A BuhlerHongshu GuanMisti PaudelKathryne MarksIfeoluwakiisi AdejoorinJeong YeeJack EllrodtSara TedeschiJeffrey SparksSiobhan M CaseTiffany HsuDaniel H SolomonA Helena JonssonRoberta Vezza AlexanderDeepak A RaoMay Y ChoiKaren H Costenbader

Published in: Journal of autoimmunity (2024)

In this sample, having COVID-19 infection in the earlier (pre-2/1/2021) vs. later pandemic was associated with more CTD symptoms, ANA positivity, and autoantibody reactivities. Earlier SARS-CoV-2 variants circulating in a less vaccinated population with less natural immunity may have been more immunogenic.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
sleep quality
multiple sclerosis
copy number
gene expression
dna methylation
physical activity