Stratification of unresponsive patients by an independently validated index of brain complexity.
Casarotto SilviaAngela ComanducciMario RosanovaSimone SarassoMatteo FecchioMartino NapolitaniAndrea PigoriniAdenauer G CasaliPietro D TrimarchiMelanie BolyOlivia GosseriesOlivier BodartFrancesco CurtoCristina LandiMaurizio MariottiGuya DevalleSteven LaureysGiulio TononiMarcello MassiminiPublished in: Annals of neurology (2016)
Given its high sensitivity and specificity in the benchmark and MCS population, PCI offers a reliable, independently validated stratification of unresponsive patients that has important physiopathological and therapeutic implications. In particular, the high-PCI subgroup of VS patients may retain a capacity for consciousness that is not expressed in behavior. Ann Neurol 2016;80:718-729.