Single-cell transcriptomes of kidneys in a 6-month-old boy with Denys-Drash syndrome reveal stromal cell heterogeneity in the tumor microenvironment.

Tao LiJiangfeng ZhouHaiyan WuXiucheng GaoQiyang ShenRui ChengMingshun Zhang

Published in: Clinical kidney journal (2023)

was identified in an infant with DDS. scRNA-Seq revealed the heterogenicity of cellular components in Wilms tumors and kidney tissues, shedding light on the pathogenesis of DDS.

Keyphrases

single cell
rna seq
high throughput
gene expression
bone marrow
case report
stem cells
dna methylation