Co-self-assembly of multiple DNA origami nanostructures in a single pot.
Joshua A JohnsonVasiliki KolliopoulosCarlos E CastroPublished in: Chemical communications (Cambridge, England) (2021)
Simultaneous self-assembly of two distinct DNA origami nanostructures folded with the same scaffold strand was achieved in a single pot. Relative yields were tuned by adjusting concentrations of the competing strands, correlating well with folding kinetics of individual structures. These results can faciliate efficient fabrication of multi-structure systems and materials.