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Co-self-assembly of multiple DNA origami nanostructures in a single pot.

Joshua A JohnsonVasiliki KolliopoulosCarlos E Castro
Published in: Chemical communications (Cambridge, England) (2021)
Simultaneous self-assembly of two distinct DNA origami nanostructures folded with the same scaffold strand was achieved in a single pot. Relative yields were tuned by adjusting concentrations of the competing strands, correlating well with folding kinetics of individual structures. These results can faciliate efficient fabrication of multi-structure systems and materials.
Keyphrases
  • single molecule
  • circulating tumor
  • cell free
  • tissue engineering
  • nucleic acid
  • molecular dynamics simulations
  • aqueous solution