FNDC5/irisin improves the therapeutic efficacy of bone marrow-derived mesenchymal stem cells for myocardial infarction.

Jingyu DengNing ZhangYong WangChao YangYabin WangChao XinJinming ZhaoZhitao JinFeng CaoZheng Zhang

Published in: Stem cell research & therapy (2020)

The present study indicated that irisin or FNDC5 improved BM-MSC engraftment and paracrine effects in infarcted hearts, which might provide a potential therapeutic target for MI.

Keyphrases

bone marrow
heart failure
mesenchymal stem cells
left ventricular
cord blood