A prospective study comparing Itraconazole alone versus systemic steroids alone as adjuncts to topical steroids in the post-operative management of Allergic fungal rhinosinusitis.

Itraconazole was comparable to Methylprednisolone in preventing disease recurrence in the post-operative management of AFRS. It may be a viable alternative to replacing systemic steroids where the latter may be contraindicated. Itraconazole given at a dose of 400 mg once daily for six weeks was a safe dose.