Adult-onset mitochondrial movement disorders: a national picture from the Italian Network.

V MontanoD OrsucciV CarelliC La MorgiaM L ValentinoC LampertiS MarchetO MusumeciA ToscanoG PrimianoF M SantorelliC TicciM FilostoA RubegniT MonginiP ToninS ServideiR CeravoloG SicilianoMichelangelo Mancuso

Published in: Journal of neurology (2021)

Movement disorders, mainly ataxia and parkinsonism, are important findings in adult primary mitochondrial diseases. This study underlies the importance of looking for a mitochondrial etiology in the diagnostic flowchart of a movement disorder and may help direct genetic screening in daily practice.

Keyphrases

oxidative stress
quality improvement
healthcare
primary care
physical activity
parkinson disease
genome wide
gene expression
copy number
dna methylation
young adults